Jewish leaders are to join dignitaries as construction begins of a permanent museum in the former Warsaw Ghetto.
Prime Minister Lech Kaczynski will attend a ground-breaking ceremony for the museum, which will mark over 1,000 years of Jewish history in Poland.
Poland was home to an estimated 3.5m Jews before World War II, with 400,000 of them in what became known as the Warsaw Ghetto.
Most were killed by the Nazis, and Poland's Jews now number about 100,000.
Half of the six million Jews killed in the Holocaust were from Poland, and the country itself was the site of some of the most notorious Nazi German death camps, including Auschwitz-Birkenau, Treblinka and Sobibor.
The new museum will be built next to a memorial for the Jews of Warsaw who resisted Nazi rule.
The museum will focus on the history of Poland's Jewish community, which dates back to the 10th Century, as well as the story of the Nazi occupation and the Holocaust.
Construction is expected to take two years with the official opening scheduled for 2010.